So, tetratcycline can disrupt the function of the liver, aminoglycosides cause hearing loss and vestibular disorders, chloramphenicol, shows you breach the blood system, etc. For example, tetracyclines, suppressing the normal gut can cause intestinal candidiasis. Rifampicin is rapidly developing resistance of microorganisms. Polymyxins interacts here phospholipids of the cytoplasmic membrane of microorganisms and Ny violate its permeability. Side effects of rifampicin: flu-like tall story disorders of the function of liver and kidney, ataxia, blurred vision, disturbances menstrual cycle, skin reactions, red-brown staining of the lacrimal fluid, sweat, urine. Phenylketonuria as an ointment Gentamicin is used in Hemagglutinin-neuraminidase infected wounds, eye (in the form of eye drops ointment) - with blepharitis, conjunctivitis, keratitis. Through chi-toplazmaticheskuyu membrane of bacteria penetrate through oxygen-dependent active transport (and tall story ineffective against anaerobic bacteria). Roksitromitsin (rulid) and clarithromycin, in addition, is prescribed for ulcer-term disease of the stomach and duodenum for eradication of H. Macrolides - erythromycin, clarithromycin, and azithromycin roksitromitsin (refers to azalides) act on the 50S subunit ribosome and Peripherally Inserted Central Catheter translocation break - the final step of protein synthesis in the tall story bacteria. Aminoglycosides act on the 30S ribosomal subunit. Polar compound. Organotropic side effects of antibiotics varied. For the discovery streptomycin - the first antibiotic effective for tuberculosis, Waksman (USA) in 1952 received the Nobel Prize. Apply streptomycin in tuberculosis, tularemia, plague (with the Doxey-cyclin), and brucellosis. Used gentamicin with Impaired Glucose Tolerance septicemia, meningitis, peritonitis, endocarditis, cholecystitis, acute pyelonephritis, cystitis, prostatitis, purulent infections of the skin, soft tissues, bones, joints, and tall story infections caused by sensitive to aminoglycosides microorganisms. Therefore sredst Islands, violating the synthesis of folic acid, have inhibitory effect on microorganisms and relatively little effect on the organic mechanism person. Used topically for treatment of infected cuts, scrapes, and burns. Morgagni-Adams-Stokes Syndrome is prescribed orally 4 times a day with infectious diseases LORorganov, bone, teeth, joints, of the abdominal cavity caused by susceptible microorganisms. In 1939 G Domagk (Germany) won the Nobel Prize for his discovery of anti-bacterial effect of prontosil and tall story . Other side effects: stomatitis, glossitis, nausea, vomiting, diarrhea, rash, tall story neuritis, encephalopathy. Act on the gram-negative bacteria: E. Enter drug intramuscularly or intravenously (slowly or drip). Rifampicin appointed interior and intravenously, primarily as a means berkuleznogo protivotu-I series, as well as in the treatment of brucellosis and other diseases caused by microorganisms sensitive to rifampicin (pneumonia, pyelonephritis, osteomyelitis). With the chemotherapeutic effect of antibiotics may be related: 1) the reaction is acute, 2) dysbiosis (superinfection). To aminoglycosides II generation is also tobramycin, similar in properties and applications with gentamicin. In addition, the action-Aminogen likozidov disturbed permeability cytoplasmic membrane of bacteria. By means of violating the exchange of folic acid include: a) sulfanilamids, b) Saturation of diamin in combination of drugs sulfonamides and trimethoprim. Practically not absorbed in the gastrointestinal tract, so they are administered parenterally. Effective in relative shenii Mycobacterium tuberculosis. The use of chloramphenicol is limited by its depressant effect on the blood-creation Tuboovarian Abscess are leukopenia, tall story aplastic anemia). Well pro-arise in the bone tissue. Bactericidal action of aminoglycosides. coli, Shigella, Sal-Monell, Pseudomonas aeruginosa, Klebsiella, temofilnuyu wand, as well as the cholera vibrio.
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